Dermalogica Phyto Nature e² Review
| Dermalogica Phyto Nature e² |
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£148
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PLEASE NOTE: I am a Skin Expert, Facialist and Dermalogica stockist and was not gifted this product or paid by Dermalogica to give a honest review. This page contains affiliate links. Making a purchase via my affiliate link means I may receive a small share of the sale.
As a skincare expert and just turned 46 years old, I know the importance of regular exfoliation and the use of resurfacing products to encourage our skin cells to regenerate and reproduce. As we age our skin cell turnover rate starts to slow leaving our skin dull, rough and not functioning very well causing premature and accelerated skin ageing. Also all our cells have a place and part to play but never did I consider our skin cells communication!
Well Dermalogica, as always is one step ahead of the skincare game and has everything under control. Dermalogica has all the answers when it comes to helping our skin calls to function better and younger with their latest New Phyto Nature E² that directly helps our cells communicate better using new science, Enzymes, and Exosomes.
Dermalogica’s Phyto Nature E² Regenerating Daily Exosome Leave On Treatment sits firmly in the “next‑generation of anti‑ageing and skin longevity” bracket, promising to resurface and renew skin with plant‑derived exosomes and gentle enzymes rather than harsh acids or scrubs.
For anyone in their late 30s and upwards who are chasing smoother texture, fewer fine lines and a brighter complexion, without needles, this at home 'leave on' treatment is a very interesting addition to any home skincare routine.
Product Overview
Phyto Nature E² is a light textured, leave on exfoliant that combines a regenerative exosome blend with pumpkin enzymes and other botanicals to accelerate the skin’s natural renewal process and trigger skin cells to actually act and function better - This is so exciting.
It’s positioned as a daily treatment for visible signs of ageing, dullness, uneven texture and loss of firmness, with independent clinical data claiming visible reduction in ageing signs within two weeks and smoother, brighter skin with continued use.
What Happens When Our Skin Starts To Age?
Our surface renewal cell turnover slows and extends - 12-25 days in our 20’s to 40 days in our 40’s and 50+ days in our 50's.
Cell communication weakens - Signal cells that talk and control communication from cell to cell start to weaken, leaving the skin to work under par and not efficient enough.
What Does This Really Mean?
More cell buildup - Dull looking skin that has difficulty with absorbing active ingredients.
Weaker signals - Slower renewal, slower repair, fine lines and less firmness.
The Search For Skin Longevity
As a skincare expert and facialist I know that cell renewal starts with exfoliation, but it doesn't end there. Helping our cells to respond, communicate and act efficiently and in a younger fashion will increase skin longevity. This is where Exosomes come into play.
Exosomes are biological living cells transforming the future of skincare. They help support the skin’s natural ability to renew itself. Exosomes act as messengers like an Army Commander In Charge Of Productivity Of Cells, helping to restore communication between cell to cell which is a vital role in the skin’s ability to function.
Phyto Nature E² combines plant based Exosome and Enzyme technology to support skin renewal, resilience and visible vitality, rapidly diminishing the appearance of fine lines, wrinkles, re-energise skin to restore visible firmness and luminosity.
Sizes and Availability
The treatment is currently priced at £148 and comes in a 100ml glass bottle with pump, which Dermalogica sells directly online and through authorised dermalogica stockists like myself. 100mls lasts for 4+ months using twice a day.
It ships with standard next day delivery options when ordered before cut off times, and the brand offers a 30 day money back guarantee, which is useful given the price point.
Suitable Skin Types
Dermalogica recommends Phyto Nature E² for mature, ageing or dull complexions looking to improve fine lines, texture and radiance, particularly for those who want results without injectables or invasive procedures.
It can be suitable for sensitive skin, but the brand advises patch testing and starting slowly (once daily or every other day) if your barrier is reactive or you already use retinoids and strong acids.
How to Use
The brand suggests using Phyto Nature E² as the first leave on step after cleansing, toning and exfoliation both morning and night (please see below)
When To Layer
- Step 1 - Precleanse
- Step 2 - Cleanse
- Step 3 - Exfoliate
- Step 4 - Toner
- Step 5 - Regenerate - PHYTO NATURE E²
- Step 6 - Serum
- Step 7 - Eyes
- Step 8 - Moisturise
- Step 9 - SPF
After your usual double cleansing (and optional Daily Microfoliant if you still like a scrub), tone and then apply two pumps to clean, dry skin.
Applying to your face, neck and upper chest (dè colletage) let it absorb fully, then layer serums, moisturiser and, in the morning, a broad spectrum SPF such as Dynamic Skin Recovery SPF50.
So skincare can be very confusing, especially when it comes to layering products. Well, I'm here to help you.
I have written a blog, that will take you step by step through each layer and in which order is best. By the end of the blog, you should feel more confident with your home skincare routine and understand where your products fit nicely into this easy plan.
To read my blog click below ⬇️
For enhanced anti ageing results, Dermalogica recommends pairing it with Phyto Nature Firming Serum and Phyto Nature Oxygen Cream.
Key Ingredients
The hero components are:
- Regenerative Exosome Blend – plant‑derived exosomes that support regeneration across multiple layers of the skin’s surface, helping to visibly reduce fine lines and wrinkles.
- Pumpkin Enzyme – a gentle exfoliating enzyme that breaks down dead skin cells to reveal smoother, brighter skin without the irritation of traditional scrubs.
- Botanical Renewal Complex (phyto glycogen + prickly pear) – works to boost natural exfoliation and smoothness.
- Bio‑fermented Acetyl Glucosamine – hydrates and offers antioxidant protection, helping to support a more resilient barrier.
The formula also includes lactic acid, so it’s not purely enzyme‑based; this means it delivers mild chemical exfoliation alongside the enzyme action.
Benefits
- Clears dull surface cells
- Supports natural skin regeneration
- Visibly smooths fine lines and wrinkles
- Two technologies, one daily step - for brighter, firmer, younger-looking skin
How It Works
The regenerative Exosome blend mimics our natural cell messengers released by cells. they deliver proteins, lipids and genetic material that help activate our own skin repair and regeneration responses. Exosomes restore skin vitality and boost visible renewal.
Exosomes also support recovery after stress or professional treatments, strengthens skin communication for improved cell function.
Clinical Test Results
Dermalogica states that over time Phyto Nature E² gives you 6 years back by diminishing the look of fine lines and smooths the texture for our skin, leaving it looking and acting younger after just 1 use** Turning the clock back on signs of ageing.
**Consumer perception results after 1 use. Based on an 8 week independent clinical study with 32 subjects, 2 applications/day.
Dermalogica's Sustainability Goals
If like me you are someone that wants to support sustainability then Dermalogica is the brand for you.
By 2025, Dermalogica is committed to achieving or exceeding the following sustainability goals:
- 90% of our ingredients will be sourced from suppliers with verified sustainable practices*
- 100% of our tubes, bottles, and boxes will be designed for reuse, recycling, and/or composting
- The majority of plastic used in our packaging will come from recycled or plant-based materials**
- We will primarily partner with suppliers who actively monitor and manage their carbon footprint***
Dermalogica Is A Brand You Can Trust
I fully put my love and trust into the skincare brand Dermalogica and have done for over 25 years.
I use only Dermalogica on my own skin and also in the salon on my clients. I really wouldn't use any other brand, I really appreciate Dermalogica's vision and ethics as there are completely Cruelty Free certified by PETA, Certified Vegan and uses NO artificial colours or fragrances.
Dermalogica's Phyto Nature Franchise
Also keep in mind ageing isn't just genetics, research now shows that more than 50% of visible signs of skin ageing comes from our environment and lifestyle. Factors like climate, UV exposure, pollution, sleep, diet and stress are chronically unhealthy, they can accelerate skin ageing beyond what DNA alone would dictate.
Cell Senescence is when previously healthy skin cells start to release toxins that accelerate skin ageing also the skin's oxygen levels can become depleted, this results in dull, tired appearance on our skins.
Ageing skin appears as wrinkled and mottled with areas of hyper-and hypopigmentation. We might also notice a general loss of elasticity, increased fragility, and benign lesions such as keratosis and dilated capillaries.
Close examination can also reveal a reduction in the density and organisation of elastin fibres and collagen - both key structures responsible for maintaining skin resilience and firmness. As these structures degrade, skin begins to sag and its ability to bounce back diminishes.
This visible decline in elasticity highlights the need for regeneration - not just surface exfoliation, but the reactivation of skin's own renewal processes. Regeneration is the skin's natural process of renewing itself (replacing older cells and supporting the production of skin-renewing compounds). This helps maintain skin's texture, tone, and overall healthy-looking appearance.
Regeneration happens continuously, but its pace and efficiency can be influenced by factors like age, environment, and lifestyle.
This is where the Dermalogica's Phyto Nature Franchise comes in to help combat the negative effects of our environment and lifestyle by addressing the damage that leads to premature and accelerated skin ageing. All having formulas to reawaken, firm, lift and defend against future damage.
See The Full Phyto-Nature Franchise - CLICK HERE
Sets Available Which Include Phyto Nature E²
Dermalogica offers a Phyto Nature Face & Eye Firming Trio Set is a great way to purchase a set of 3 amazing Dermalogica Phyto Nature Firming products that compliment each other perfectly while also receiving 10% OFF
This set consists of Three Full Size Phyto Nature top selling Dermalogica's Products:
- Phyto Nature E² - 100ml
- Phyto Nature Lifting Eye Cream - 15ml To Read My Phyto Nature Lifting Eye Cream Review - Click Here
- Phyto Nature Oxygen Cream - 50ml To Read My Blog - Why Does Our Skin Need Oxygen - Click Here
Cost
In the UK, Phyto Nature E² is priced at £148.00 for 100 ml, lasting 4+ months using twice a day, placing it firmly in the luxury skincare bracket but feel it is completely worth it with all the next generation ingredients and technologies found in one dual acting leave on treatment.
While the cost per millilitre is high, around £1.48 per ml the brand positions it as a “multi‑tasking” daily treatment that replaces or reduces the need for separate exfoliants and some anti ageing serums, which may also justify the spend for regular users.
Where To Buy
You can buy it direct from Dermalogica on their website.
My Review
I have been using the Phyto Nature E² for over 6 weeks now and absolutely love it. I love the light water based texture that is absorbed easily into my skin leaving it smooth and feeling plump. I have definitely noticed my skin feeling healthier and looking younger with a natural inner glow and firmness to it. I love the new science in this product that is working on a deep cellular level, working with my skin to help the cells function better and act younger and I feel very certain this product is going to help me to age slower and more gracefully, helping to prevent me moving onto and then relying on injectables.
I have full trust and belief in the brand Dermalogica and have done for over 27 years now and would never deviate into any other brands. I trust that Dermalogica always has skin health at the forefront of all they products.
Conclusion
Phyto Nature E² is a high‑end, daily leave on exfoliant that uses the power of science and next generation of ingredients including plant‑based exosomes and enzymes to smooth texture, brighten tone and soften fine lines, rather than aggressive acids.
Phyto Nature E² suits everyone with ageing, dull or uneven skin who want gradual, long‑term improvement and are comfortable investing in a premium product.
For younger or very sensitive skin that doesn’t yet need this level of intervention it maybe better to look into other products in Dermalogica's Phyto Nature Franchise.
While it is a premium product, the results speak for themselves and the quality of the ingredients makes it a worthy investment for those seeking visible, lasting improvements and skin longevity.
Thank you for taking the time to read my review and I hope you have found it informative and inspires you to try Dermalogica's Phyto Nature E².
If you have any questions or comments please leave a message below.
love nicola x
| Dermalogica Phyto Nature e² |
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£148
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